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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633665Generated: October 30, 2026

Methanesulfonyl chloride → Methanesulfonic acid 5-[1-(4-ethynyl-phenyl)-1H-indol-5-yl]-pent-4-ynyl ester

https://huagongshe.com/reaction/1633665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
ReactantHCID 18679523HCID 18679523—
ProductMethanesulfonic acid 5-[1-(4-ethynyl-phenyl)-1H-indol-5-yl]-pent-4-ynyl esterHCID 86585592—

Reaction Steps

In analogyto example 5.4, 5-[1-(4-Ethynyl-phenyl)-1H-indol-5-yl]-pent-4-yn-1-ol and methanesulfonyl chloride were converted to yield Methanesulfonic acid 5-[1-(4-ethynyl-phenyl)-1H-indol-5-yl]-pent-4-ynyl ester as orange oil, MS: 377 (M).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06503907B2
Source datasetuspto-grants-2003_01
ORD IDord-31dcd64697254f44a42a86a164a3abfa
Source noteuspto-grants-2003_01