1,4-Dibromobutane → HCID 18679520, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH3:11])=[CH:5]2.[Br:12][CH2:13][CH2:14][CH2:15][CH2:16]Br>>[Br:12][CH2:13][CH2:14][CH2:15][CH2:16][O:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH3:11])=[CH:5]2Participants
3
Procedure
In analogy to example 3.1, 5-hydroxy-2-methylindole and 1,4-dibrombutane were converted to yield 5-(4-Bromo-butoxy)-2-methyl-1H-indole as colorless solid, mp 85° C., MS: 281 (M, 1Br).
Sources & evidence
- ORD record
- ord-a9ad1badf7f848f88cae78638b766fdf
- Source dataset
- uspto-grants-2003_01
- Patent number
- US06503907B2
Reaction notes
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