HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Ethyl-2-propyn-1-ylamino)ethanol → 2-(Ethyl-{3-[1-(4-fluoro-phenyl)-1H-indol-5-yl]-prop-2-ynyl}-amino)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Ethyl-2-propyn-1-ylamino)ethanol | HCID 249874 | — |
| Reactant | Trifluoro-methanesulfonic acid 1-(4-fluoro-phenyl)-1H-indol-5-yl ester | HCID 86585583 | — |
| Product | 2-(Ethyl-{3-[1-(4-fluoro-phenyl)-1H-indol-5-yl]-prop-2-ynyl}-amino)-ethanol | HCID 18679565 | — |
Reaction Steps
In analogy to example 17.3, Trifluoro-methanesulfonic acid 1-(4-fluoro-phenyl)-1H-indol-5-yl ester and 2-(Ethyl-prop-2-ynyl-amino)-ethanol were converted to yield 2-(Ethyl-{3-[1-(4-fluoro-phenyl)-1H-indol-5-yl]-prop-2-ynyl}-amino)-ethanol as brown viscous oil, MS: 337 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06503907B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-daf2d0daf5d24fc589bca0c0e88376f1 |
| Source note | uspto-grants-2003_01 |