4-Fluoroiodobenzene → HCID 18679484, compound

HRID 1633704Notes

Reaction equation

HRID 1633704 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[F:11])[NH:7][CH:6]=[CH:5]2.[F:12][C:13]1[CH:18]=[CH:17][C:16](I)=[CH:15][CH:14]=1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[F:11])[N:7]([C:16]1[CH:17]=[CH:18][C:13]([F:12])=[CH:14][CH:15]=1)[CH:6]=[CH:5]2

Participants

3

Reactant 2

HCID 96054-FluoroiodobenzeneHCID 116871455-bromo-6-fluoro-1H-indole

Product 1

HCID 18679484HCID 18679484, compound

Procedure

In analogy to example 23.3, 5-Bromo-6-fluoro-1H-indole and 1-fluoro-4-iodobenzene were converted to yield 5-Bromo-1-(4-fluoro-phenyl)-6-fluoro-1H-indole as a light yellow solid, MS: 307 (M, 1Br).

Sources & evidence

ORD record
ord-536b51ea960543d4a006d1f40ae38016
Source dataset
uspto-grants-2003_01
Patent number
US06503907B2

Reaction notes

Loading…