HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylamino)ethanol → 2-({4-[1-(4-Chloro-phenyl)-6-fluoro-1H-indol-5-yloxy]-butyl}-methyl-amino)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylamino)ethanol | HCID 8016 | — |
| Reactant | 5-(4-Bromo-butoxy)-1-(4-chloro-phenyl)-6-fluoro-1H-indole | HCID 18679485 | — |
| Product | 2-({4-[1-(4-Chloro-phenyl)-6-fluoro-1H-indol-5-yloxy]-butyl}-methyl-amino)-ethanol | HCID 10271726 | — |
Reaction Steps
In analogy to example 23.7, 5-(4-Bromo-butoxy)-1-(4-chloro-phenyl)-6-fluoro-1H-indole and 2-(methylamino)ethanol were converted to yield 2-({4-[1-(4-Chloro-phenyl)-6-fluoro-1H-indol-5-yloxy]-butyl}-methyl-amino)-ethanol as a colorless oil, MS: 391 (MH+,1Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06503907B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-511a078f1e6d4f52afcd7e53dc041371 |
| Source note | uspto-grants-2003_01 |