2-(Ethylamino)ethanol → HCID 10271593, compound

HRID 1633709Notes

Reaction equation

HRID 1633709 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][C:15]=1[F:16])[N:12]([C:17]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=1)[CH:11]=[CH:10]2.[CH2:24]([NH:26][CH2:27][CH2:28][OH:29])[CH3:25]>>[F:23][C:20]1[CH:21]=[CH:22][C:17]([N:12]2[C:13]3[C:9](=[CH:8][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:26]([CH2:24][CH3:25])[CH2:27][CH2:28][OH:29])=[C:15]([F:16])[CH:14]=3)[CH:10]=[CH:11]2)=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 80722-(Ethylamino)ethanolHCID 18679425HCID 18679425, compound

Product 1

HCID 10271593HCID 10271593, compound

Procedure

In analogy to example 23.7, 5-(4-Bromo-butoxy)-1-(4-fluoro-phenyl)-6-fluoro-1H-indole and 2-(ethylamino)ethanol were converted to yield 2-({4-[1-(4-Fluoro-phenyl)-6-fluoro -1H-indol-5-yloxy]-butyl}-ethyl-amino)-ethanol as light yellow oil, MS: 389 (MH+).

Sources & evidence

ORD record
ord-9dfa7516ddfb47b790ef774109d7d75c
Source dataset
uspto-grants-2003_01
Patent number
US06503907B2

Reaction notes

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