HCID 15546131, compound → HCID 15546132, compound

Participants

Reaction Steps

The purified protected triphosphate 12 was taken up in concentrated aqueous NH4OH (4 mL) and stirred for 2.5 h at room temperature. The reaction mixture was concentrated to give compound 13 which was formulated with 0.1 M TEAB pH 7.0 to a concentration of 2.6 mM. The concentration and purity of the formulated bulk were confirmed by UV/Vis spectroscopy and analytical ion pair HPLC as described above, respectively. See FIG. 8.

Provenance & Evidence