HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1633962Generated: October 30, 2026
p-(Trifluoromethoxy)phenyl isocyanate → HCID 23550123, compound
https://huagongshe.com/reaction/1633962
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-(Trifluoromethoxy)phenyl isocyanate | HCID 92298 | — |
| Reactant | HCID 22502125 | HCID 22502125 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Solvent | Diisopropylethylamine | HCID 81531 | — |
| Product | HCID 23550123 | HCID 23550123 | — |
Reaction Steps
Ethyl 3-(4-Aminomethylbenzoylamino)propanoate hydrochloride (0.25 g, 0.87 mmol) in acetonitrile (5 mL) and diisopropylethylamine (0.15 mL) was allowed to react with 4-trifluoromethoxyphenylisocyanate (0.37 g, 1.74 mmol) at 50° C. overnight. Upon cooling to 25° C. the product precipitated and was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06503949B1 |
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| Source dataset | uspto-grants-2003_01 |
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| ORD ID | ord-9518547eb2344ad68774dd5f9ba97e69 |
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| Source note | uspto-grants-2003_01 |
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