反应详情

To a solution of 3-methylsulfonylbenzoic acid (10 g, 50 mmol) in anhydrous methanol (100 mL) was added conc. sulfuric acid (10 mL). The mixture was refluxed for 4 hours and then concentrated to one-third volume. Water (200 mL) was added, and the mixture was extracted with diethyl ether. The organic extract was washed with 10% sodium carbonate solution, and dried over Na2SO4. After concentration, 8.6 g (81%) of methyl 3-methylsulfonylbenzoate was obtained.

1. temperatureThe mixture was refluxed for 4 hours
2. concentrationconcentrated to one-third volume
3. additionWater (200 mL) was added
4. extractionthe mixture was extracted with diethyl ether
5. extractionThe organic extract
6. washwas washed with 10% sodium carbonate solution
7. dry with materialdried over Na2SO4
8. concentrationAfter concentration