Imidazole → HCID 11790200, compound

Temperature

80 °C

A solution was prepared by adding 9.5 g of imidazole (0.14 mol) to 200 mL of water while stirring with a stir bar. Then 5.8 g of sodium hydroxide were added to the imidazole solution dropwise while stirring. After complete dissolution of the sodium hydroxide, the solution was added dropwise over a 15 minute period to a stirred aqueous solution of 20 g (0.07 mol) of zinc sulfate-hexahydrate in 1000 mL of water. Immediately a white precipitate formed. Stirring continued for 3 hours with heating to 80° C. Then the solution was cooled to room temperature. The product was collected in a Büchner funnel lined with a paper filter, and washed with 50 mL of water, 50 mL of methanol and finally with 50 mL of diethyl ether. The white solid was dried for 16 hours in an oven heated at 50° C.

1. customA solution was prepared
2. stirringwhile stirring
3. customImmediately a white precipitate formed
4. stirringStirring
5. temperatureThen the solution was cooled to room temperature
6. customThe product was collected in a Büchner funnel
7. filtrationfilter
8. washwashed with 50 mL of water, 50 mL of methanol and finally with 50 mL of diethyl ether
9. customThe white solid was dried for 16 hours in an oven
10. temperatureheated at 50° C.

ORD record

ord-bd0c945b11214a0fa866c57e5bdff7e1

Source dataset

uspto-grants-2003_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06506494B2