HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 4-Bromomethyl-benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Bromomethyl-benzoyl chloride | HCID 5068289 | — |
Reaction Steps
4-bromomethylbenzoic acid (25 g, 116.25 mmol) was dissolved in CH2Cl2 (200 ml) and treated with oxalyl chloride (12.2 ml, 139.5 mmol). DMF (0.45 ml) was added slowly then stirred for 1 h. The solvent was removed to give the 4-bromomethylbenzoyl chloride as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506738B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-7a28937f8b074991be7b078142b639c1 |
| Source note | uspto-grants-2003_01 |