HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634021Generated: October 30, 2026
Dimethylamine → 4-(bromomethyl)-N,N-dimethylbenzamide
https://huagongshe.com/reaction/1634021
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Bromomethyl-benzoyl chloride | HCID 5068289 | — |
| Product | 4-(bromomethyl)-N,N-dimethylbenzamide | HCID 18677023 | 99.7% |
Reaction Steps
A mixture of 4-bromomethyl-benzoyl chloride (7.0 g, 30.24 mmol), polyvinyl pyridine (9.6 g, 90.7 mmol) and dimethyl amine (15.9 ml, 31.8 mmol, 2.0 M in THF) was stirred at 23° C. for 15 h. The solution was filtered and the solvent removed to give 7.3 g (99% yield) of 4-bromomethyl-N,N-dimethyl-benzamide as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06506738B1 |
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| Source dataset | uspto-grants-2003_01 |
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| ORD ID | ord-b0a94fe1c5d54929915b223100cce8e7 |
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| Source note | uspto-grants-2003_01 |
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