Water → Ethyl 1-(4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl)cyclobutanecarboxylate
Reaction equation
[Cl:31][CH:32]([Cl:33])[Cl:34].[NH2:1][c:2]1[c:3]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:4][c:5]([C:8]2([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH2:11]2)[cH:6][cH:7]1.[O:23]=[C:24]1[N:25]([Br:30])[C:26](=[O:27])[CH2:28][CH2:29]1.[OH2:35]>>[NH2:1][c:2]1[c:3]([O:17][CH2:18][C:19]([F:20])([F:21])[F:22])[cH:4][c:5]([C:8]2([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:9][CH2:10][CH2:11]2)[cH:6][c:7]1[Br:30]Participants
5
Sources & evidence
- ORD record
- ord-f3c908f657154671936316561ae0e892
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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