Toluene → HCID 86584758, compound

Participants

Reaction Steps

125 mg (0.323 mmol) of 2,5-bis-(4-chlorophenyl-methoxy)benzaldehyde, 68.3 mg (0.355 mmol) of rhodanine-3-acetic acid, 18 mg (0.125 mmol) of piperidine acetate and 10 ml of toluene were heated on a water separator under a nitrogen atmosphere for 4 hours. Subsequently, the reaction mixture was evaporated, the residue was taken up in ethyl acetate, washed several times with water, dried and again evaporated. The residue was triturated with diethyl ether and filtered off under suction: 125 mg (69%) of the title compound; 1HNMR (DMSO-d6, 250 MHz) δ 7.92 (s, 1H), 7.49 (m, 8H), 7.20 (m, 2H), 7.00 (m, 1H), 5.22 (s, 2H), 5.18 (s, 2H), 4.57 (s, 2H); TLC (toluene/methyl ethyl ketone/glacial acetic acid (72:20:8)): Rf=0.51.

Provenance & Evidence