5-Methylfurfural → HCID 86758789, compound

HRID 1634214Notes

Reaction equation

HRID 1634214 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([CH2:8][NH:9][C:10]([CH:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:11])[CH:5]=[C:4]([NH2:17])[N:3]=1.C1(C)C=C(C)C=C(C)C=1S([NH:29]O)(=O)=O.[CH3:32][C:33]1[O:37][C:36]([CH:38]=O)=[CH:35][CH:34]=1>>[NH2:17][C:4]1[N:3]2[N:29]=[C:38]([C:36]3[O:37][C:33]([CH3:32])=[CH:34][CH:35]=3)[N:1]=[C:2]2[CH:7]=[C:6]([CH2:8][NH:9][C:10]([CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)=[O:11])[CH:5]=1

Participants

4

Reactant 3

HCID 120975-MethylfurfuralHCID 11009332O-mesitylenesulfonylhydroxylamineHCID 86758787HCID 86758787, compound

Product 1

HCID 86758789HCID 86758789, compoundYield 27%

Procedure

The title compound was prepared in accordance with the general method of example 365 from cyclopentanecarboxylic acid (2,6-diamino-pyridin-4-ylmethyl)-amide, o-mesitylene-sulfonylhydroxylamine, and 5-methyl-2-furaldehyde. The purification was performed with column chromatography on silica eluting with dichloromethane/ethylacetate 1:2.

Workup

  1. customThe purification

Sources & evidence

ORD record
ord-f1730a0c2eb143c9af12d2687cc41512
Source dataset
uspto-grants-2003_01
Patent number
US06506772B1

Reaction notes

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