Ethanol → HCID 12035491, compound

HRID 1634233Notes

Reaction equation

HRID 1634233 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]1[N:11]([CH3:29])[C:12]2[C:21]3[C:20](=[O:22])[NH:19][C:18]([CH3:23])=[C:17]([CH2:24][C:25]([OH:27])=[O:26])[C:16]=3[CH:15]=[CH:14][C:13]=2[N:28]=1.[CH2:30](O)[CH3:31]>OS(O)(=O)=O>[CH2:30]([O:26][C:25](=[O:27])[CH2:24][C:17]1[C:16]2[CH:15]=[CH:14][C:13]3[N:28]=[C:10]([NH:9][C:3]4[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=4[Cl:8])[N:11]([CH3:29])[C:12]=3[C:21]=2[C:20](=[O:22])[NH:19][C:18]=1[CH3:23])[CH3:31]

Participants

4

Reactant 2

HCID 702EthanolHCID 11070040HCID 11070040, compound

Product 1

HCID 12035491HCID 12035491, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Prepared from 2-(2,6-dichlorophenylamino)-1,7-dimethyl-9-oxo-1,8-dihydro-imidazo[4,5-h]isoquinolin-6-yl acetic acid by refluxing in ethanol and H2SO4. Mp 280-285° C. (dec); MS(CI) 459, 461 (MH+).

Sources & evidence

ORD record
ord-35783b771c35400ba1c0ef3a8944e6b3
Source dataset
uspto-grants-2003_01
Patent number
US06506769B2

Reaction notes

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