HCID 69843388, compound → HCID 11070550, compound

Participants

Reaction Steps

To a solution of the product of Example 12 (30 mg, 0.06 mmol) in EtOH (3 mL) and AcOH (4 mL) in a Parr reactor was added PtO2 (2 mg, 0.007 mmol). The Parr reactor was charged with 50 psi of H2 and shaken for 12 h. The crude reaction was filtered through diatomaceous earth with EtOH and concentrated in vacuo. Column chromatography (2% MeOH—CH2Cl2) provided the title compound (9 mg, 30%), mp 268° C.(dec); MS(ES) 459, 461 (MH+).

Provenance & Evidence