HCID 10237539, compound → HCID 10193967, compound

HRID 1634290Notes

Reaction equation

HRID 1634290 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[C:9]3[C:10]([CH:22]([CH2:24][C:25]([N:27]([CH3:29])[CH3:28])=O)[O:23][C:7]=2[CH:6]=[CH:5][CH:4]=1)=[C:11]1[C:16](=[CH:17][CH:18]=3)[NH:15][C:14]([CH3:20])([CH3:19])[CH:13]=[C:12]1[CH3:21].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(OCC)C>[CH3:1][O:2][C:3]1[C:8]2[C:9]3[C:10]([CH:22]([CH2:24][CH2:25][N:27]([CH3:29])[CH3:28])[O:23][C:7]=2[CH:6]=[CH:5][CH:4]=1)=[C:11]1[C:16](=[CH:17][CH:18]=3)[NH:15][C:14]([CH3:19])([CH3:20])[CH:13]=[C:12]1[CH3:21]

Participants

4

Reactant 2

HCID 10237539HCID 10237539, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 10193967HCID 10193967, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of Example 63 in diethyl ether was reduced at room temperature with lithium aluminum hydride to provide the desired compound.

Sources & evidence

ORD record
ord-945ce46ea5e54e8f8061261e276a58df
Source dataset
uspto-grants-2003_01
Patent number
US06506766B1

Reaction notes

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