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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634341Generated: October 31, 2026

(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine → (2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine dihydrochloride

https://huagongshe.com/reaction/1634341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidineHCID 15549737—
Reactant(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 86757653—
Product(2S,3S)-3-(2-Methoxy-5-(2,2,2-trifluoroethyl)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 70000775—

Reaction Steps

This compound was prepared from Compound 48 in the same manner of Compound 28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06506775B1
Source datasetuspto-grants-2003_01
ORD IDord-53e264463f7e4cd1a05debe52af54977
Source noteuspto-grants-2003_01