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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634364Generated: November 2, 2026

(2S,3S)-3-((6-Methoxy-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidine → (2S,3S)-3-((6Methoxy-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidine dihydrochloride

https://huagongshe.com/reaction/1634364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-((6-Methoxy-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidineHCID 44593634—
Reactant(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 86757653—
Product(2S,3S)-3-((6Methoxy-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-7-yl)methyl)amino-2-phenylpiperidine dihydrochlorideHCID 70000778—

Reaction Steps

This compound was prepared from Compound 93 in the same manner of Compound 28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06506775B1
Source datasetuspto-grants-2003_01
ORD IDord-e59556fd034c487985c0549a67fab941
Source noteuspto-grants-2003_01