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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634367Generated: October 30, 2026

(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochloride → 5-[(1-Chloro-1-(trifluoromethyl)ethyl]-2-methoxybenzylamino]-2-phenylpiperidine dihydrochloride

https://huagongshe.com/reaction/1634367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-(5-(1,1-Difluoroethyl)-2-(trifluoromethoxy)benzyl)amino-2-phenylpiperidine dihydrochlorideHCID 86757653—
Reactant5-[(1-Chloro-1-(trifluoromethyl)ethyl]-2-methoxybenzylamino]-2-phenylpiperidineHCID 86757658—
Product5-[(1-Chloro-1-(trifluoromethyl)ethyl]-2-methoxybenzylamino]-2-phenylpiperidine dihydrochlorideHCID 86757657—

Reaction Steps

This compound was prepared from Compound 104 in the same manner of Compound 28.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06506775B1
Source datasetuspto-grants-2003_01
ORD IDord-3a3c2ddc003e493cbdb06dc10892634c
Source noteuspto-grants-2003_01