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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634396Generated: October 26, 2026

3,5-Difluorophenylacetic acid → HCID 178496843, compound

https://huagongshe.com/reaction/1634396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant2-(1-Aminoethyl)-1-tert-butoxycarbonyl-4-methoxycarbonyl-4-phenyl-2-imidazolineHCID 22592446—
ProductHCID 178496843HCID 178496843—

Reaction Steps

Following General Procedure C above and using 3,5-difluorophenylacetic acid (Aldrich) and 1-tert-butoxycarbonyl-2-(1-aminoethyl)-4-methoxycarbonyl-4-phenyl-2-imidazoline (Example K), the title compound was prepared as a white foam (90%). The reaction was monitored by tlc (Rf=0.39 in 3:2 hexanes/EtOAc) and the product was purified by flash column chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06506782B1
Source datasetuspto-grants-2003_01
ORD IDord-574dcade2ff04b119c721317aa96bfc6
Source noteuspto-grants-2003_01