Dimethylformamide diethylacetal → HCID 69859264, Verbindung

HRID 1634633Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1634633
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:5][CH:4]=1.C(O[CH:18](OCC)[N:19]([CH3:21])[CH3:20])C>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9](=[CH:18][N:19]([CH3:21])[CH3:20])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:7][CH:8]=1

Komponenten

3

Edukt 2

HCID 70913Dimethylformamide diethylacetalHCID 84174Ethyl 4-methoxyphenylacetate

Produkt 1

HCID 69859264HCID 69859264, Verbindung

Reaktionsbedingungen

Temperatur
135 °C

Versuchsvorschrift

2 g (0.0103 mol) of ethyl p-methoxyphenylacetate and 9.1 g (10.6 ml, 0.0618 mol) of dimethylformamide diethylacetal were mixed in a 100 ml balloon flask provided with reflux cooler, magnetic stirring and thermometer. The thus obtained solution was heated to reflux (135° C.) for 20 hours. Then the dimethylformamide diethylacetal and the unreacted ethyl p-methoxyphenylacetate were removed by distillation under vacuum, the desired product being obtained as distillation residue. 2,14 g of ethyl α-(p-methoxyphenyl)-β-(dimethylamino)acrylate were thus obtained (Yield: 83%).

Aufarbeitung

  1. customprovided
  2. temperaturewith reflux cooler
  3. temperatureThe thus obtained solution was heated
  4. customThen the dimethylformamide diethylacetal and the unreacted ethyl p-methoxyphenylacetate were removed by distillation under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-4bb7062c8f4944789919d344d8f26605
Quelldatensatz
uspto-grants-2003_01
Patentnummer
US06506941B1

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