HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → (S)-2-Methyl-4-oxiranylmethoxy-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Hydroxy-2-methylindole | HCID 590225 | — |
| Reactant | (S)-(+)-Glycidyl-4-nitrobenzoate | HCID 10868995 | — |
| Product | (S)-2-Methyl-4-oxiranylmethoxy-1H-indole | HCID 59032962 | 50.7% |
Reaction Steps
Prepared from 2-methyl-4-hydroxyindole (5 g, 33 mmol), (S)-glycidyl nosylate (8.78 g, 33 mmol) and potassium carbonate (4.56 g, 33 mmol) according to the procedure used for Intermediate 1 to give 3.4 g product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-753d4d369ca844e7b1d07eb58be9d3b5 |
| Source note | uspto-grants-2003_01 |