反应详情

温度

235 °C

A mixture of 4-methoxy-2-oxindole (3.5 g, 21.4 mmol) and 3.0 g of aluminum chloride was heated at 235° C. for 10 minutes with stirring. On cooling the sludge was triturated with H2O. The solids were filtered washed with H2O and dried to give 3.0 g of product as an orange solid. Purified by flash chromatography (hexane-ethyl acetate 3:1) to give 1.1 g of pure title compound.

1. temperatureOn cooling the sludge
2. customwas triturated with H2O
3. filtrationThe solids were filtered
4. washwashed with H2O
5. customdried