HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18678579, compound → 4-(2-Hydroxy-3-{[1-(3,3,3-trifluoro-propyl)-piperidin-4-ylmethyl]-amino}-propoxy)-fluoren-9-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18678579 | HCID 18678579 | — |
| Reactant | 4-[(2S)-oxiranylmethoxy]-9-fluorenone | HCID 59032967 | — |
| Product | 4-(2-Hydroxy-3-{[1-(3,3,3-trifluoro-propyl)-piperidin-4-ylmethyl]-amino}-propoxy)-fluoren-9-one | HCID 23553507 | 58.5% |
Reaction Steps
Prepared from 4-[(2S)-oxiranylmethoxy]-9-fluorenone (0.087 g, 0.34 mmol) and 4-aminomethyl-1-(3,3,3-trifluoropropyl)-piperidine (0.126 g, 0.6 mmol) of according to the procedure used for Example 2 to give 0.092 g of the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-9ddd617a27c6485d99d7ddd9553594df |
| Source note | uspto-grants-2003_01 |