HCID 4184048, compound → 1-Pentyl-4-piperidinemethanamine

HRID 1634770Notes

Reaction equation

HRID 1634770 reaction equation
[CH2:1]([N:6]1[CH2:11][CH2:10][CH:9]([C:12]([NH2:14])=O)[CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH2:14][CH2:12][CH:9]1[CH2:10][CH2:11][N:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[CH2:7][CH2:8]1

Participants

3

Reactant 2

HCID 4184048HCID 4184048, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 186785741-Pentyl-4-piperidinemethanamineYield 79%

Procedure

Prepared from 1-pentyl-piperidine-4-carboxamide (3.0 g, 15.1 mmol) and LAH (1.14 g, 30.2 mmol) according to general the procedure used for Example 8 (Step B) to give 2.2 g of title compound as an oil.

Sources & evidence

ORD record
ord-6afd5fcc2dac4b0caf6ed6d5cbd697f5
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

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