HCID 18678532, compound → HCID 18678389, compound

HRID 1634778Notes

Reaction equation

HRID 1634778 reaction equation
[CH2:1]([N:14]1[CH2:19][CH2:18][CH:17]([C:20]([NH2:22])=O)[CH2:16][CH2:15]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH2:22][CH2:20][CH:17]1[CH2:18][CH2:19][N:14]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 18678532HCID 18678532, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 18678389HCID 18678389, compoundYield 80.4%

Procedure

Prepared from 1-tridecylpiperidine-4-carboxamide (4.7 g, 15.1 mmol) and LAH (1.14 g, 30.0 mmol) according to general procedure used for Example 8 (Step B) to give 3.6 g of title compound as a pale yellow solid.

Sources & evidence

ORD record
ord-f8954cb4c6a54898b24836b55f72a90e
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

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