HCID 18678656, compound → HCID 18678663, compound

HRID 1634781Notes

Reaction equation

HRID 1634781 reaction equation
[CH2:1]([N:16]1[CH2:21][CH2:20][CH:19]([C:22]([NH2:24])=O)[CH2:18][CH2:17]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH2:24][CH2:22][CH:19]1[CH2:20][CH2:21][N:16]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH2:17][CH2:18]1

Participants

3

Reactant 2

HCID 18678656HCID 18678656, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 18678663HCID 18678663, compoundYield 104.3%

Procedure

Prepared from 1-pentadecylpiperidine-4-carboxamide (4.3 g, 12.7 mmol) and LAH (0.97 g, 21.2 mmol) according to general procedure used for Example 8 (Step B) to give 4.3 g of title compound as a pale yellow solid.

Sources & evidence

ORD record
ord-956d3e9f0deb4a668ea5867cec2f4d5d
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

Loading…