4-Piperidinecarboxamide → HCID 18678498, compound

HRID 1634783Notes

Reaction equation

HRID 1634783 reaction equation
[NH:1]1[CH2:9][CH2:8][CH:4]([C:5]([NH2:7])=[O:6])[CH2:3][CH2:2]1.Br[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][OH:23]>>[OH:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][N:1]1[CH2:9][CH2:8][CH:4]([C:5]([NH2:7])=[O:6])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 37724-PiperidinecarboxamideHCID 13789512-Bromo-1-dodecanol

Product 1

HCID 18678498HCID 18678498, compoundYield 68.7%

Procedure

Prepared from isonipecotamide (2.0 g, 15.6 mmol), 12-bromododecanol (4.15 g, 15.6 mmol) potassium carbonate and (2.16 g, 15.6 mmol) according to procedure used for Example 8 (Step A) to give 3.35 g of the title compound as a white solid.

Sources & evidence

ORD record
ord-adcb07f6080544508d4993b1566886ed
Source dataset
uspto-grants-2003_01
Patent number
US06506901B2

Reaction notes

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