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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1634786Generated: October 30, 2026

(S)-(+)-4-(2,3-Epoxypropoxy)carbazole → (2S)-1-(9H-Carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol

https://huagongshe.com/reaction/1634786

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-(+)-4-(2,3-Epoxypropoxy)carbazoleHCID 10879208—
ReactantHCID 18678703HCID 18678703—
Product(2S)-1-(9H-Carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-olHCID 10118955124.9%

Reaction Steps

Prepared from 4-[(2S)-Oxiranylmethoxy]-9H-carbazole (0.125 g, 0.52 mmol) and (4-aminomethyl-1-piperidinyl) 4-methoxybenzenesulfonamide (0.255 g, 0.9 mmol) according to procedure used for Example 2 to give 0.170 g of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06506901B2
Source datasetuspto-grants-2003_01
ORD IDord-39285ee184834e81bafe3416e591040f
Source noteuspto-grants-2003_01