HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(+)-4-(2,3-Epoxypropoxy)carbazole → (2S)-1-(9H-Carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(+)-4-(2,3-Epoxypropoxy)carbazole | HCID 10879208 | — |
| Reactant | HCID 18678703 | HCID 18678703 | — |
| Product | (2S)-1-(9H-Carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol | HCID 10118955 | 124.9% |
Reaction Steps
Prepared from 4-[(2S)-Oxiranylmethoxy]-9H-carbazole (0.125 g, 0.52 mmol) and (4-aminomethyl-1-piperidinyl) 4-methoxybenzenesulfonamide (0.255 g, 0.9 mmol) according to procedure used for Example 2 to give 0.170 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-39285ee184834e81bafe3416e591040f |
| Source note | uspto-grants-2003_01 |