HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18678703, compound → (2S)-1-(3-Chloro-9H-carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18678703 | HCID 18678703 | — |
| Reactant | 3-Chloro-4-[(2S)-oxiranylmethoxy]-9H-carbazole | HCID 59032959 | — |
| Product | (2S)-1-(3-Chloro-9H-carbazol-4-yloxy)-3-{[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol | HCID 10231234 | 122.2% |
Reaction Steps
Prepared from 3-chloro-4-[(2S)-oxiranylmethoxy]-9H-carbazole (0.060 g, 0.22 mmol) and (4-aminomethyl-1-piperidinyl) 4-methoxybenzenesulfonamide (0.125 g, 0.5 mmol) according to procedure used for Example 2 to give 0.075 g of the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-7007eab2e7bf45979910a9904ccee04e |
| Source note | uspto-grants-2003_01 |