t-butyl-[4-(2S)-oxiranylmethoxy-phenoxy]-diphenylsilane → 4-((2S)-2-Hydroxy-3-{[1-(1-methyl-1H-imidazole-4-sulfonyl)-piperidin-4-ylmethyl]-amino}-propoxy)-phenol

Participants

Reaction Steps

Prepared from t-butyl-[4-(2S)-oxiranylmethoxy-phenoxy]-diphenylsilane (0.404 g, 1.0 mmol) and [1-(1-methyl-1H-imidazole-4-sulfonyl)-piperidin-4-ylmethyl amine (0.650 g, 1.8 mmol) according to the procedure used in example 37 to give 0.045 g of the title compound as a white solid.

Provenance & Evidence