Acetic Acid → HCID 10283807, compound

Participants

Reaction Steps

The title compound was prepared from N-[5-(2-amino-1-{R}-hydroxyethyl)-2-hydroxyphenyl]-methanesulfonamide (0.128 g, 0.52 mmol), (4-{3-[4-(4-formyl-piperidine-1-sulfonyl)-phenyl]-ureidomethyl}-3-fluoro-phenoxy)-acetic acid methyl ester (0.5 mmol), glacial acetic acid (0.03 mL, 0.5 mmol) and sodium cyanoborohydride (0.031 g, 0.5 mmol) according to the general procedure used for example 84 (Step E) to give the final product (0.21 g).

Provenance & Evidence