HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosulfonic acid → 4-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Reactant | 1,3-Dihydro-1-methyl-3-phenyl-2H-imidazol-2-one | HCID 19798330 | — |
| Product | 4-(3-Methyl-2-oxo-1-imidazolidinyl)benzenesulfonyl chloride | HCID 18678416 | — |
Reaction Steps
A solution of 1-methyl-3-phenylimidazol-2-one (5.7 g, 32.3 mmol) in 10 mL of chlorosulfonic acid was stirred at ambient temperature for 30 minutes. The reaction mixture was poured into ice/water and extracted with ethyl acetate. The organic phase was separated, dried (Na2SO4) and concentrated in vacuo to a white solid (7.4 g). Used as is in the following prep.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-f32be6f8ac794ae786cde1bc3dc3445f |
| Source note | uspto-grants-2003_01 |