HCID 70001049, compound → HCID 59032968, compound

Participants

Reaction Steps

A mixture of (2R)-2-{[4-(4-({[(2R)-2-hydroxy-2-{4-hydroxy-3-[(methylsulfonyl)-amino]-phenyl}ethyl)amino]methyl}piperidin-1-yl)benzoyl]-amino}butanedioic acid dibenzyl ester (0.110 g, 0.14 mmol) and 0.11 g of 10% palladium on carbon in ethanol (3 mL) and cyclohexene (1 mL) was heated at reflux for 3 hours. When complete, the catalyst was filtered (Celite) and the cake was washed with hot methanol. The solvent was removed under reduced pressure, to give the title compound (0.010 g).

Provenance & Evidence