N-methyl-2-pyrrolidone → HCID 59620855, compound

Participants

Reaction Steps

Into 120 g of N-methyl-2-pyrrolidone were dissolved 11.5 g of 1-amylnaphthalene, and then 3.74 g of sodium amide were added to the resultant solution while the solution was stirred at room temperature. Into the solution were added 1.20 g of sodium iodide as a catalyst and 0.89 g of 2,5-di-t-butylhydroquinone as a polymerization inhibitor. Thereafter, 13.4 g of p-chloromethylstyrene were added thereto over 30 minutes. The resultant solution was stirred at room temperature for 2 hours, and then 200 ml of chloroform were added thereto and dissolved. The solution was washed 3 times with water. The solvent was removed from the chloroform phase. The residue was purified by column chromatography to yield 11.6 g of p-vinylbenzylnaphthylamine as an intermediate.

Provenance & Evidence