3,4,5-Trimethoxybenzeneboronic acid → Ethyl 2-(3,4,5-trimethoxyphenyl)pyridine-4-carboxylate

HRID 1634878Notes

Reaction equation

HRID 1634878 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5](B(O)O)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].Cl[C:17]1[CH:18]=[C:19]([CH:25]=[CH:26][N:27]=1)[C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:17]2[CH:18]=[C:19]([CH:25]=[CH:26][N:27]=2)[C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 27343903,4,5-Trimethoxybenzeneboronic acidHCID 2762942Ethyl 2-chloroisonicotinate

Product 1

HCID 16125879Ethyl 2-(3,4,5-trimethoxyphenyl)pyridine-4-carboxylate

Procedure

3,4,5-Trimethoxyphenylboronic acid (15.29 g) and ethyl 2-chloroisonicotinate (13.39 g) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-3ee0747e7f3b4b8aa8cb18b2bace9659
Source dataset
uspto-grants-2003_01
Patent number
US06509329B1

Reaction notes

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