4-Chloro-6-methylpyrimidine → HCID 18546794, compound

HRID 1634903Notes

Reaction equation

HRID 1634903 reaction equation
Cl[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13](B(O)O)[CH:14]=[C:15]([O:19][CH3:20])[C:16]=1[O:17][CH3:18]>>[CH3:8][C:6]1[CH:7]=[C:2]([C:13]2[CH:12]=[C:11]([O:10][CH3:9])[C:16]([O:17][CH3:18])=[C:15]([O:19][CH3:20])[CH:14]=2)[N:3]=[CH:4][N:5]=1

Participants

3

Reactant 2

HCID 5817964-Chloro-6-methylpyrimidineHCID 27343903,4,5-Trimethoxybenzeneboronic acid

Product 1

HCID 18546794HCID 18546794, compound

Procedure

4-Chloro-6-methylpyrimidine (913 mg) and 3,4,5-Trimethoxyphenylboronic acid (2.73 g) were reacted in the same manner as in Preparation Example 1 to obtain the title compound.

Sources & evidence

ORD record
ord-45ce983083fa474b884a36f10c852da2
Source dataset
uspto-grants-2003_01
Patent number
US06509329B1

Reaction notes

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