3-Bromobenzene-1-sulfonamide → 3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]-oxazin-6-yl)benzenesulfonamide

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Reaction Steps

Prepared according to procedure B from 3-bromobenzenesulfonamide and (1,4-dihydro-4,4-dimethyl-2-oxo-2H-3,1-benzoxazin-6-yl) boronic acid. White solid: mp 242-244° C. (dec) 1H-NMR (DMSO-d6) δ10.28 (s, broad 1H), 8.07 (s,1H), 7.9 (d, 1H, J=7.80 Hz), 7.78 (d, 1H J=7.86 Hz), 7.64 (t, 1H, J=7.79 Hz), 7,59 (m, 2H), 7.42 (s, broad 2H), 7.02 (d, 1H, J=8.86 Hz), 1.68 (s, 6H); MS m/z 331(M+H). Anal. Calc. for C16H16N2O4S: C,57.82, H, 4.85, N, 8.43. Found: C, 57.49, H,5.08, N, 8.05.

Provenance & Evidence