反应详情

4-Chloro-3-methoxy-2-methyl-pyridine (6.12 g) is dissolved in carbon tetrachloride (80 ml) then N-bromo-succinimide (7.12 g) and benzoyl peroxide (1 g) are added. The reaction mixture is refluxed under UV irradiation for 1.5 hour. The solid is filtered after cooling and the solvent evaporated. The desired product is purified by chromatography on silica gel.

1. temperatureThe reaction mixture is refluxed under UV irradiation for 1.5 hour
2. filtrationThe solid is filtered
3. temperatureafter cooling
4. customthe solvent evaporated
5. customThe desired product is purified by chromatography on silica gel