Furan-3-boronic acid → tert-Butyl (4-(furan-3-yl)-2-nitrophenyl)carbamate

HRID 1635136Notes

Reaction equation

HRID 1635136 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[O:19]1[CH:23]=[CH:22][C:21](B(O)O)=[CH:20]1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:21]2[CH:22]=[CH:23][O:19][CH:20]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2734358Furan-3-boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Product 1

HCID 69592767tert-Butyl (4-(furan-3-yl)-2-nitrophenyl)carbamate

Procedure

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and furan-3-boronic acid according to the general procedure B. Obtained as an orange solid (855 mg).

Sources & evidence

ORD record
ord-97a57f26c2b74188b6b4ae2ce541d153
Source dataset
uspto-grants-2003_01
Patent number
US06509328B1

Reaction notes

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