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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1635145Generated: October 26, 2026

2,4-Difluorophenylboronic acid → (2',4'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/1635145

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorophenylboronic acidHCID 2734334—
ReactantTert-butyl (4-iodo-2-nitrophenyl)carbamateHCID 23554339—
Product(2',4'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl esterHCID 69592801—

Reaction Steps

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 2,4-difluorobenzene boronic acid according to the general procedure B. Obtained as a yellow solid (3.26 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06509328B1
Source datasetuspto-grants-2003_01
ORD IDord-2608648fa7f8435a9920c919acc46d10
Source noteuspto-grants-2003_01