HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → (2-Amino-4-thiazol-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | (2-Nitro-4-thiazol-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester | HCID 69592841 | — |
| Product | (2-Amino-4-thiazol-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester | HCID 69592761 | 58% |
Reaction Steps
Prepared from (2-nitro-4-thiazol-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester (Example F7) (205 mg, 0.59 mmol) by reduction with SnCl2.2H2O (668 mg, 2.95 mmol) according to the general procedure G (method b). Obtained as a yellow solid (108 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509328B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-9cd1b6deeb6641569bca6d846a4f443c |
| Source note | uspto-grants-2003_01 |