HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2',3'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester → (3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2',3'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester | HCID 69592780 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester | HCID 69592847 | 101.4% |
Reaction Steps
Prepared from (2′,3′-difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example B19) (3.14 g, 8.96 mmol) by catalytic hydrogenation with Pd/C according to the general procedure G (method a). Obtained as a green solid (2.91 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509328B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-a8720243fc474a8e97a5862ca574caa8 |
| Source note | uspto-grants-2003_01 |