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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1635255Generated: October 30, 2026

Trifluoroacetic anhydride → HCID 22224751, compound

https://huagongshe.com/reaction/1635255

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic anhydrideHCID 9845—
Reactant3-(2-Cyano-pyridin-4-yl)-3-oxo-propionic acid tert-butyl esterHCID 69592816—
SolventTFA acetoneHCID 86586799—
ProductHCID 22224751HCID 22224751—

Reaction Steps

Prepared from 3-(2-cyano-pyridin-4-yl)-3-oxo-propionic acid tert.-butyl ester (Example H10) by stirring in TFA/acetone with TFAA according to general procedure J (method b). Obtained as a brown solid (3.30 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06509328B1
Source datasetuspto-grants-2003_01
ORD IDord-5aa43376c3434c619b23310d17b445f3
Source noteuspto-grants-2003_01