HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-6-(3-trifluoromethyl-phenyl)-[1,3]dioxin-4-one → HCID 86588011, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-6-(3-trifluoromethyl-phenyl)-[1,3]dioxin-4-one | HCID 22224716 | — |
| Reactant | Carbamic acid,[2-amino-4-[6-(phenylmethoxy)-3-pyridinyl]phenyl]-,1,1-dimethylethyl ester | HCID 69592766 | — |
| Product | HCID 86588011 | HCID 86588011 | 67.6% |
Reaction Steps
Prepared from [2-amino-4-(6-benzyloxy-pyridin-3-yl)-phenyl]-carbamic acid tert.-butyl ester (Example G30) (203 mg, 0.52 mmol) and 2,2-dimethyl-6-(3-trifluoromethyl-phenyl)-[1,3]dioxin-4-one (Example J5) (150 mg, 0.55 mmol) according to the general procedure K. Obtained as an off-white solid (213 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509328B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-dea07b2268a6419c87eaa01f80778c66 |
| Source note | uspto-grants-2003_01 |