Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester → {2',3'-Difluoro-3-[3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester | HCID 69592847 | — |
| 반응물 | 3-Oxo-3-(3-[1,2,3)triazol-1-yl-phenyl)-propionic acid ethyl ester | HCID 69592868 | — |
| 생성물 | {2',3'-Difluoro-3-[3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester | HCID 86588079 | — |
반응 단계
Prepared from (3-amino-2′,3′-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G49) (160 mg, 0.5 mmol) and 3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionic acid ethyl ester (Example H2) (130 mg, 0.5 mmol) according to the general procedure K. Obtained as an amorphous yellow substance (166 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06509328B1 |
| 출처 데이터셋 | uspto-grants-2003_01 |
| ORD ID | ord-d641a44935ba491bb9afb38142e28a0d |
| 출처 메모 | uspto-grants-2003_01 |