HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22224841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86601096 | HCID 86601096 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22224841 | HCID 22224841 | — |
Reaction Steps
Prepared from [2-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert.-butyl ester (Example K98) (307 mg, 0.62 mmol) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a eggshell solid (146 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509328B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-32487d06017b44c39ba0465573406286 |
| Source note | uspto-grants-2003_01 |