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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1635535Generated: October 29, 2026

4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy [1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]piperidin-4-ol → 4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-ethoxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidine

https://huagongshe.com/reaction/1635535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy [1]benzoxepino [2,3-b]pyridin-5-ylidene)propyl]piperidin-4-olHCID 66757538—
Reactant4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-hydroxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidineHCID 66757949—
Product4-(4-Chlorophenyl)-1-[3-(5,11-dihydro-7-ethoxy[1]benzoxepino[2,3-b]pyridin-5-ylidene)propyl]piperidineHCID 66758353—

Reaction Steps

The titled compound was prepared by following the procedure of example 46, but replacing the product of example 44 with the product of example 151.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06509346B2
Source datasetuspto-grants-2003_01
ORD IDord-31673f5537f847c3a539f3425967eda0
Source noteuspto-grants-2003_01